Large-scale production of vaccines, monoclonal antibodies, insulin, recombinant proteins, and more.
The stainless steel bioreactor is a vessel designed for bioprocess applications, typically constructed from high-grade stainless steel. It offers excellent strength, corrosion resistance, high-temperature tolerance, and ease of cleaning, making it ideal for various biological processes such as cell culture and microbial fermentation.
Stainless steel bioreactors play a critical role in bioprocessing by providing a controlled operating environment, efficient oxygen transfer, effective mixing, ease of operation and cleaning, and scalability for large-volume production. These advantages make them essential equipment widely used in the biotechnology and pharmaceutical industries.
Used in food processing, textiles, detergents, lactase production, and other enzymes.
Bioreactors/fermentation systems are ideal for the production of most industrial enzymes, typically through submerged liquid fermentation (batch, fed-batch, or continuous) using bacteria, yeast, or fungi.
Stainless steel vessels are used for media preparation, mixing, and storage.
Biological inactivation systems are employed to treat waste broth and exhaust gases after fermentation, which may contain large quantities of engineered or highly active wild-type strains.
CIP systems are essential for thoroughly cleaning fermenters, preparation tanks, and piping systems, effectively removing residual media, enzymes, and biomass to prevent cross-contamination between batches or different enzyme productions, thereby ensuring the purity and efficiency of subsequent fermentations.
Heat exchangers are used for precise temperature control during fermentation (as temperature has a significant impact on microbial growth and enzyme synthesis rates); for thermal inactivation or cooling after fermentation; and for energy-efficient heat recovery.
Production of beneficial microorganisms such as biofertilizers and biopesticides.
Bioreactors are used for large-scale fermentation of beneficial microorganisms (e.g., nitrogen-fixing bacteria, phosphate-solubilizing bacteria, and biocontrol agents such as Bacillus subtilis, Trichoderma spp., and Bacillus thuringiensis [Bt]). These systems provide optimal growth conditions for high-density cultivation.
Stainless steel vessels are used for the preparation, mixing, and storage of culture media or nutrient solutions.
Biowaste inactivation systems are designed to treat waste broth and exhaust gases—especially critical when using engineered strains, highly active microbes, or potentially pathogenic biocontrol fungi. These systems prevent the unintentional release of viable microorganisms into the environment, avoiding ecological contamination and harm to non-target organisms.
CIP cleaning systems are used to clean fermenters, preparation tanks, and related equipment. They effectively remove residual organic matter and microorganisms, prevent contamination by unwanted microbes, and ensure the purity and activity of target strains in subsequent production batches.
Cellular agriculture that produces meat by cultivating animal cells in bioreactors.
Bioreactors are used for large-scale suspension culture of animal cells (such as muscle and fat stem cells), aiming to achieve high-density cell proliferation and high volumetric productivity.
Heat exchangers are used to precisely control the temperature within the bioreactor—for preheating the culture medium before it enters the reactor or cooling the harvested liquid.
Applied in the production of hyaluronic acid, vitamins, xanthan gum, biodegradable materials, etc.
Fermenters enable batch, fed-batch, or continuous cultivation of bacteria, yeast, and fungi for the production of various bioproducts.
Stainless steel vessels are used for large-scale media preparation, mixing, and storage. They can serve as seed tanks, main fermenters, or fermentation liquid storage tanks, and are also used for material pretreatment, precipitation, and crystallization (e.g., calcium citrate precipitation), as well as media sterilization.
